Table 1. Characteristics of the study cohort.
| Gp 1, ART Naive |
Gp 2, Virologically Suppressed on ART |
Gp 3 Healthy Controls |
P- value | ||
|---|---|---|---|---|---|
| Number | 102 | 172 | 63 | - | |
| Gender, M/F | 47/55 | 116/56 | 22/41 | ||
| Age (in years) | 36.5 ±5.8 | 38.6 ±5.9 | 36.8 ±7.09 | ||
| Median duration of infection; (in mo.) (range) |
15 (2–42) |
72 (39.5–92) |
NA | <0.001* (Gp1 vs Gp 2) |
|
| Mean Nadir CD4+ T-cell count, cells/ μL; (range) | NA | 312.3 ± 199 (5–1425) |
NA | __ | |
| Mean CD4+ T-cell count at study entry; cells/ μL) ± SD (range) | 421.4 ± 321.6 (21–1897) |
743.4 ± 321.6 (154–1863) |
NA | <0.001* | |
| Median Duration of ART in months; (range) | __ | 43 (22–72) |
NA | __ | |
| Body Mass Index (Kg/m2); Median (range) | 22.7 (20.1–26.3) |
22 (19–25.8) |
24.6 (22.5–27.1) |
0.013* (Gp1vs3) 0.006*(Gp 2vs3) |
|
All descriptive variables are provided as median and interquartile ranges except for age, Nadir CD4 and CD4 counts at entry which are provided as mean ± SD. T-test was used to calculate p-value between the groups for ‘age’ which was normally distributed, while Mann-Whitney U-test was used for other non-normally distributed variables.
* indicates statistical significance.