Table 1. Altered metabolic pathways after TBI in gray and white brain matter.

Pathway	GM 2m/s; 6mm	WM 2m/s; 6mm	GM 4m/s; 6mm	WM 4m/s; 6mm	GM 4m/s; 12mm	WM 4m/s; 12mm	GM 4m/s; 15mm	WM 4m/s; 15mm
Citrate cycle (TCA cycle)					+
Glycolysis or Gluconeogenesis					+		+
Methane metabolism					+		+
Glyoxylate and dicarboxylate metabolism					+		+
Pyruvate metabolism	+		+		+		+
Cysteine and methionine metabolism				+		+		+
Lysine degradation		+		+		+		+
Pantothenate and CoA biosynthesis		+		+		+
Phenylalanine metabolism		+		+		+
Starch and sucrose metabolism				+		+		+
Butanoate metabolism					+	+	+	+
Glycerolipid metabolism		+		+	+	+	+	+
Arachidonic acid metabolism	+		+		+	+	+	+
AminoacyltRNA biosynthesis				+				+
Alanine, aspartate and glutamate metabolism	+	+	+	+	+
Arginine and proline metabolism	+	+	+	+	+	+	+	+
Galactose metabolism	+	+	+	+	+	+	+	+
Glycine, serine and threonine metabolism	+	+	+	+	+	+	+	+
Inositol phosphate metabolism	+	+	+	+	+	+	+	+

Note: + = significantly altered after TBI based on impact-value threshold set to 0.1