Table 2. Altered metabolic pathways after TBI in serum 24 hours and 7 days post-TBI.

Pathway	2m/s; 6mm 24 hours	2m/s; 6mm 7 days	4m/s; 6mm 24 hours	4m/s; 6mm 7 days	4m/s; 12mm 24 hours	4m/s; 12mm 7 days	4m/s; 15mm 24 hours	4m/s; 15mm 7 days
Glycerophospholipid metabolism	+		+		+		+
Cysteine and methionine metabolism		+				+		+
Phenylalanine metabolism		+		+				+
AminoacyltRNA biosynthesis		+		+
Pyruvate metabolism	+	+	+			+		+
Glycine, serine, and threonine metabolism	+	+		+			+	+
Pyrimidine metabolism			+
Galactose metabolism	+						+
Lysine degradation		+		+	+		+
Citrate cycle (TCA cycle)						+		+
Inositol phosphate metabolism								+
Butanoate metabolism								+
Alanine, aspartate, and glutamate metabolism	+	+	+	+	+	+		+
Arginine and proline metabolism	+	+	+	+	+	+	+

Note: + = significantly altered after TBI based on impact-value threshold set to 0.1