Table 4. Summary statistics for case/control expression differences in whole blood for genes identified in DNA methylation analyses.

Gene	FDR (limma)	p-value (limma)	p-value (linear fit)	Moderated log fold change (limma)	Log fold change (linear fit)
SLFN12	3.29e-09	2.25e-10	4.88e-11	-0.417	-0.599
HLA-DRB1	7.98e-12	3.17e-13	1.28e-13	-0.302	-0.442
NINJ2	1.97e-05	3.64e-06	1.83e-09	-0.186	-0.349
LOC100049716	0.527	0.446	0.046	-0.038	-0.123

Genome-wide analysis (limma) and individual linear fit coefficients and p-values are listed, as well as limma p-values adjusted for multiple hypothesis testing to control the false discovery rate (FDR). Limma moderates fold changes and hence represent more conservative coefficients and p-values than linear fit.