Table 1.
Overview of IL-6 Actions
| Acute phase response |
| Hypothalamic-pituitary-adrenal axis |
| Fever |
| Hormone release |
| Immune cell maturation and activation |
| Immunoglobulin production by B cells |
| Proliferation and differentiation of T cells |
| Hemostasis |
| Platelet production from megakaryocytes |
| Hematopoesis |
| Endothelial cell activation |
| Neuronal cell differentiation |
| Keratinocyte proliferation |
| Cardiac muscle hypertrophy |
| Osteoclast activation |
Abbreviation: IL-6, interleukin-6.