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. 2018 Aug 1;7(9):e1471440. doi: 10.1080/2162402X.2018.1471440

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Figure 6. — ASTX660 stimulates cytotoxic T lymphocyte killing. (A) MOC1ova cells were plated with ASTX660 (250 nM) and allowed to grow for 20 hours before addition of effector cells at indicated effector:target (E:T) ratios. (B-C) At both 1:1 and 10:1 E:T ratios, Concanamycin A (ConA, 100 nM), anti-TNFα (20 ng/mL), anti-TRAIL (20 ng/mL), and anti-FasL (20 ng/mL) were also added in addition to CTLs after 20 hours of cell growth. Impedance lines are graphed as averages of 3 replicates that have been normalized to a cell index of 1.0 at 20 hours when drugs or CTLs were added.