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Decision plots demonstrate sensitivity and specificity vs ADC value and ADC ratio for PIRADS category 3 lesions. Optimal threshold value was calculated to maximize the sum of sensitivity and specificity. For PI-RADS Category 3 lesions, these threshold values are able to provide for very high specificity for diagnosis of clinically significant peripheral zone prostate cancer. ADC, apparent diffusion coefficient; PI-RADS, Prostate Imaging-Reporting and Data System.
