Table 2.
Antiviral activity from HIV neutralisation assay
| IC50 (nM)a | CZA97 | B41 | BG505 | SF162 | MN | DU422 |
|---|---|---|---|---|---|---|
| 1 | 6.8±1.6 | 181.1±89.1 | 15.2±0.2 | 11.3±2.2 | 102.4±29.9 | 14.8±0.3 |
| 2 | 7.6±1.0 | 210.8±58.9 | 14.0±0.5 | 15.6±0.9 | 67.1±9.1 | 16.0±1.1 |
| 3 | 4.6±0.1 | 118.8±4.0 | 9.0±0.2 | 7.2±1.8 | 77.9±2.4 | 6.0±2.7 |
| 4 | 6.5±0.8 | 171.3±4.6 | 9.7±2.6 | 11.4±0.8 | 51.2±10.2 | 11.3±0.1 |
| T20 | 941.0±328.3 | 214.6±16.2 | 18.4±10.1 | 23.9±2.1 | 6.5±0.6 | 56.0±1.6 |
| AZT | 184.6±26.4 | 106.4±16.8 | 84.0±1.8 | 109.6±23.5 | 194.1±1.6 | 183.3±1.9 |
a
Antiviral activity shown as the IC50, was determined by HIV neutralization assay. Each IC50 represents the mean ± SEM obtained from at least two independent experiment.