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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Am J Med Genet C Semin Med Genet. 2018 Jul 28;178(3):326–337. doi: 10.1002/ajmg.c.31638

Figure 1. :Radiological and histopathological features of LAM.

Figure 1

1A: High-resolution chest CT images from a patient with LAM demonstrating the characteristic thin-walled, round, uniform cysts. 1B: Histopathology demonstrating a cystic air filled space (star) lined by LAM cells (arrow). 1C: High-power view demonstrating the LAM cells surrounding the cystic space. Notice the characteristic epitheloid and spindle shaped morphology of these cells. These cells stained positive for smooth muscle cell markers (stains not shown) as well as HMB-45 (1D). Histopathological images courtesy of Dani S. Zander, MD at the University of Cincinnati.