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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Curr Protoc Microbiol. 2018 Aug 20;51(1):e61. doi: 10.1002/cpmc.61

Figure 1. Molecular Combing.

Figure 1

A silane-coated glass coverslip is inserted into a DNA solution in a Teflon reservoir. The ends of the DNA molecules adhere to the coverslip, and when the coverslip is slowly pulled out, the DNA molecules are pulled straight by the surface tension between the glass and the buffer the DNA is suspended in.