TABLE I.
Baseline characteristics of patients with non-small-cell lung cancer according to BRAF V600E mutation status
| Characteristic | BRAF V600E mutation status | ||
|---|---|---|---|
|
| |||
| All | Yes | No | |
| Patients (n) | 59a | 46 | 11 |
|
| |||
| Mean age (years) | 64.5±14.5 | 65.3±10.6 | 61.1±11 |
|
| |||
| Sex (% men) | 56.6 | 63 | 45.4 |
|
| |||
| Nonsmokers (%) | 28 | 27.3 | 18.2 |
|
| |||
| PS 0–1 (%) | 82.4 | 82.5 | 77.8 |
|
| |||
| Weight loss <5% (%) | 83.9 | 86.0 | 81.8 |
|
| |||
| Adenocarcinoma (%) | 93.1 | 95 | 90 |
|
| |||
| Previous cancer (%) | 20.3 | 26 | 0 |
|
| |||
| Family history of cancer (%) | 31 | 28 | 36 |
|
| |||
| Stage IV (%) | 75 | 75 | 81.8 |
|
| |||
| Symptomatic | 84.5 | 80.0 | 100 |
|
| |||
| Main symptoms (%) | |||
| Respiratory | 75 | 80.6 | 63.6 |
| Pain | 27 | 31.4 | 18.2 |
| Neurologic | 13.7 | 8.3 | 27.3 |
| Others | 24.5 | 25.0 | 18.2 |
a
Data missing for 2 patients.