TABLE I.
Partial list of ongoing studies30
| ClinicalTrials.gov identifier | Study name | Phase |
|---|---|---|
| NCT02710253 | Salvage Radiation Therapy in Treating Patients with Metastatic Cancer That Has Progressed After Systemic Immunotherapy | II |
| NCT02400814 | Atezolizumab and Stereotactic Ablative Radiotherapy in Treating Patients with Stage IV Non-Small-Cell Lung Cancer | I |
| NCT02843165 | Checkpoint Blockade Immunotherapy with or without Stereotactic Body Radiation Therapy in Treating Patients with Primary or Metastatic Tumor | II |
| NCT01970527 | Phase II Trial of Stereotactic Body Radiotherapy Followed by Ipilimumab in Treating Patients with Stage IV Melanoma | II |
| NCT02696993 | Nivolumab and Radiation Therapy with or without Ipilimumab in Treating Patients with Brain Metastases from Non-Small-Cell Lung Cancer | I/II |
| NCT01436968 | Phase 3 Study of ProstAtak Immunotherapy with Standard Radiation Therapy for Localized Prostate Cancer | III |
| NCT02239900 | Ipilimumab and Hypofractionated Stereotactic Body Radiation Therapy in Treating Patients with Advanced Solid Malignancies | I/II |
| NCT02444741 | Pembrolizumab and Stereotactic Body Radiation Therapy or Non-stereotactic Wide-Field Radiation Therapy in Treating Patients with Non-Small-Cell Lung Cancer | I/II |
| NCT03162731 | Nivolumab, Ipilimumab, and Radiation Therapy in Treating Patients with Stage IVA-B Head and Neck Cancer | |
| NCT02437071 | Pembrolizumab with Radiation Therapy or Ablation Therapy in Treating Patients with Metastatic Colorectal Cancer | II |
| NCT03122496 | Durvalumab, Tremelimumab, and Stereotactic Body Radiation Therapy in Treating Patients with Metastatic Anaplastic Thyroid Cancer | I |
| NCT02830594 | Pembrolizumab and Palliative Radiation Therapy in Treating Patients with Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer | II |
| NCT02829931 | Hypofractionated Stereotactic Radiation Therapy and Nivolumab in Treating Patients with Recurrent High Grade Glioma | I |
| NCT02781506 | Nivolumab with or without Stereotactic Ablative Radiation Therapy in Treating Patients with Metastatic Kidney Cancer | II |
| NCT01996202 | Ipilimumab and Radiation Therapy in Treating Patients with High-Risk of Recurrence or Locally Advanced Melanoma | |
| NCT02959463 | Pembrolizumab after Radiation Therapy in Treating Patients with Pleural Malignant Mesothelioma | I |
| NCT03051672 | Pembrolizumab and Palliative Radiation Therapy in Treating Patients with Metastatic Invasive Breast Cancer | II |
| NCT02303990 | Pembrolizumab and Hypofractionated Radiation Therapy in Treating Patients with Advanced or Metastatic Cancer | I |