Table 7.
Univariate COX regression analysis
| Variable |
Overall survival |
||
| HR | 95%CI | P value | |
| Gender (man vs women) | 0.952 | 0.498-1.821 | 0.882 |
| Age (≥ 60 vs < 60) | 1.113 | 0.581-2.130 | 0.747 |
| Tumour diameter (≥ 40 mm vs < 40 mm) | 1.285 | 0.684-2.413 | 0.436 |
| Lymph metastasis (yes vs no) | 2.667 | 1.381-5.128 | 0.003 |
| Tissue differentiation (high and medium vs low) | 4.156 | 1.622-10.656 | 0.003 |
| Invasive depth (T3/4 vs T1/2) | 2.464 | 1.189-5.104 | 0.015 |
| HPA expression (positive vs negative) | 3.282 | 1.968-7.475 | 0.000 |
| MARK expression (positive vs negative) | 2.083 | 1.068-4.065 | 0.031 |
| H. pylori (positive vs negative) | 1.065 | 0.556-2.045 | 0.849 |
HPA: Heparanase; MAPK: Mitogen-activated protein kinase; H. pylori: Helicobacter pylori; HR: Hazard ratio; CI: Confidence interval.