Table 1.

Molecular classifications of human hepatocellular carcinomas

First author	Year	Number of HCCs	Number of groups	Class/subclass names	Ref.
Lee	2004	91	2	Cluster A-Cluster B	[36,37]
Boyault	2006	56	6	G1-G6	[42]
Chiang	2008	91	5	CTNNB1-proliferation	[58]
Hoshida	2009	232	3	S1-S3	[59]
Désert	2017	1133	4	PP-PV-ECM-STEM	[43]
TCGA network	2017	559	3	iCluster 1-iCluster 3	[92]

HCCs: Hepatocellular carcinomas; TCGA : The Cancer Genome Atlas; CTNNB1: Gene encoding β-catenin; PP: Periportal; PV: Perivenous; ECM: Extracellular matrix; STEM: Stem/progenitor cells.