Figure 6. S1P and DH-S1P contents in plasma, HDL, and lipoprotein-depleted fractions obtained from apoM-overexpressing mice.
Ten-week-old male C57BL/6 mice were injected with adenovirus coding apoM (ApoM) or control blank adenovirus (Null). Five days after the injection of the adenoviruses, the mice were subjected to a 6-h fast, and plasma samples were collected and subsequently separated into HDL and lipoprotein-depleted fractions. The S1P and DH-S1P levels were measured in the total plasma (A), HDL (B), and lipoprotein-depleted fractions (C); *P<0.01