Table 3.

Meta-analysis of the different models of SNCA variants in each group.

Variants	Allele (1/2)	Data	In total		European		East Asian
			DM	RM	DM	RM	DM	RM
rs181489	T/C	OR[95%CI]	1.29 [1.15, 1.45]	1.58 [1.39, 1.79]	1.26 [1.12, 1.42]	1.58 [1.38, 1.80]	–	–
		p-value	< 0.0001	<0.00001	0.0001	<0.00001	–	–
rs356165	G/A	OR[95%CI]	1.27 [1.11, 1.46]	1.48 [1.35, 1.61]	1.40 [1.24, 1.59]	1.71 [1.43, 2.05]	1.08 [0.81, 1.45]	1.42 [1.27, 1.58]
		p-value	0.0004	<0.00001	<0.00001	<0.00001	0.59	<0.00001
rs356186	A/G	OR[95%CI]	0.74 [0.66, 0.83]	0.76 [0.57, 1.03]	–	–	0.74 [0.66, 0.83]	0.76 [0.57, 1.03]
		p-value	<0.00001	0.08	–	–	<0.00001	0.08
rs356219	G/A	OR[95%CI]	1.34 [1.27, 1.41]	1.52 [1.42, 1.62]	1.30 [1.22, 1.38]	1.47 [1.36, 1.59]	1.55 [1.31, 1.83]	1.60 [1.40, 1.82]
		p-value	<0.00001	<0.00001	<0.00001	<0.00001	<0.00001	<0.00001
rs356220	T/C	OR[95%CI]	1.20 [1.07, 1.35]	1.48 [1.30, 1.68]	–	–	–	–
		p-value	0.002	<0.00001	–	–	–	–
rs2736990	G/A	OR[95%CI]	1.30 [1.14, 1.49]	1.30 [1.16, 1.45]	–	–	1.41 [1.16, 1.71]	1.25 [1.09, 1.43]
		p-value	0.0001	<0.00001	–	–	0.0006	0.001
rs2737029	G/A	OR[95%CI]	1.52 [1.27, 1.82]	1.53 [1.25, 1.87]	1.42 [1.20, 1.69]	1.37 [1.16, 1.62]	–	–
		p-value	<0.00001	< 0.0001	< 0.0001	0.0003	–	–
rs11931074	T/G	OR[95%CI]	1.43 [1.33, 1.55]	1.53 [1.39, 1.69]	1.39 [1.25, 1.55]	1.64 [1.03, 2.62]	1.43 [1.27, 1.62]	1.52 [1.37, 1.68]
		p-value	<0.00001	<0.00001	<0.00001	0.04	<0.00001	<0.00001

The results are presented as OR (95% CI). The bold characters or numbers represent the statistically significant variants and corresponding relevant data.

DM, dominant model; RM, recessive model; Allele 1, allele of corresponding variant analyzed in Table 2; OR, odds ratio; CI, confidence interval.