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Sodium butyrate down-regulates proinflammatory cytokine IL-1β expression in diabetic mice. Levels of serum cytokine IL-1β in sodium butyrate treatment (n = 9), vehicle group (n = 8) and healthy group (n = 5) mice were assessed by ELISA. The IL-1β level is increased in diabetic mice compared with normal, whereas sodium butyrate inhibit its expression. **p < 0.01 vs. healthy group, ##p < 0.01 vs. vehicle group.
