Table II.
NGAL, KIM-1, and NAG measurements in prediction of mortality risk scores and organ failure
| Parameters | AUC (95% interval confidence) | |
|---|---|---|
| Risk mortality score | Organ failure (+1) | |
| NGAL | 0.695 (0.603–0.786) | 0.841 (0.764–0.917) |
| KIM-1 | 0.745 (0.661–0.829) | 0.839 (0.769–0.909) |
| NAG | 0.694 (0.597–0.791) | 0.739 (0.644–0.833) |
| Risk mortality score | ||
| With septic non-AKI | With septic AKI | |
| NGAL | 0.811 (0.688–0.933) | 0.839 (0.731–0.946) |
| KIM-1 | 0.951 (0.907–0.995) | 0.553 (0.379–0.727) |
| NAG | 0.707 (0.557–0.857) | 0.634 (0.472–0.796) |
| Organ failure (+1) | ||
| With septic non-AKI | With septic AKI | |
| NGAL | 0.669 (0.537–0.802) | 0.578 (0.420–0.737) |
| KIM-1 | 0.763 (0.649–0.877) | 0.620 (0.465–0.775) |
| NAG | 0.641 (0.498–0.785) | 0.659 (0.505–0.813) |
Results are presented for the whole sample and for subgroups of septic patients with and without AKI. ROC – curve analysis, NGAL – neutrophil gelatinase-associated lipocalin [ng/ml], KIM-1 – kidney injury molecule-1 [ng/ml], NAG – N-acetyl-β-D-glucosaminidase [U/l].