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. 2017 Dec 31;14(6):1321–1332. doi: 10.5114/aoms.2018.72564

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Copyright: © 2017 Termedia & Banach

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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High expression of miR-216b and low expression of KRAS was beneficial for the prognosis of pancreatic cancer patients. A, B – qRT-PCR and western blot results showed that the expression levels of KRAS mRNA and protein in pancreatic cancer cell lines (BxPC-3, Panc-1, and CFPAC-1) were remarkably higher than those of normal pancreatic cell line HPDE6-C7. **P < 0.01, ***p < 0.001, compared with HPDE6-C7 cells. C, D – Kaplan-Meier survival analysis confirmed that the high expression of miR-216b and low expression of KRAS were related to the better prognosis of pancreatic cancer patients (log-rank test, all p < 0.05)