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. 2017 Dec 31;14(6):1321–1332. doi: 10.5114/aoms.2018.72564

Figure 3.

Figure 3

MiR-216b directly targeted KRAS. A – TargetScan algorithm was used to predict the binding site of miR-216b in KRAS 3′UTR. B – The luciferase activity of KRAS 3′UTR-wt in Panc-1 cells transfected with miR-216b mimics was significantly weaker compared with the cells transfected with negative control mimics. However, there was no significant difference in the luciferase activity of KRAS 3′UTRmut between the miR-216b group and NC group

**P < 0.05, compared with NC group