Table V.

Relationship between KRAS expression and clinicopathological characteristics in pancreatic cancer patients

Characteristic	Number	High expression of KRAS (n = 89)	Low expression of KRAS (n = 89)	P-value
Age [years]:				0.0961
> 60	101	56	45
≤ 60	77	33	44
Gender:				0.1327
Male	96	53	43
Female	82	36	46
Tumor location:				0.6437
Pancreatic head	110	53	57
Periampullary	68	36	32
Tumor size [cm]:				0.0089*
< 5	109	63	46
≥ 5	69	26	43
Lymphatic metastasis:				< 0.0001*
Yes	107	68	39
No	71	21	50
Neural invasion:				0.1335
Present	91	51	40
Absent	87	38	49
TNM staging:				0.0238*
Early stage (I–II)	82	33	49
Advanced (III–IV)	96	56	40

^*Categorical variables were compared by the χ² test. P < 0.05 was recognized as a significant difference.