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. 2018 Mar 28;14(6):1361–1373. doi: 10.5114/aoms.2018.74757

Table IX.

Effect βg calculated with Quanto software by regression coefficient according to three models of inheritance

Variable DBP [mm Hg] Glucose [mg/dl] HbA1c (%) CHOL [mg/dl] HDL [mg/dl] SBP [mm Hg] TRG [mg/dl] HOMA-IR BMI [kg/m2] Insulin [mU/ml]
dbSNP MAF N 406 406 408 406 406 406 406 355 409 357
Mean 77.4 102 11.2 179 49.8 143 154 2.20 31.3 6.96
SD 11.41 63.56 2.582 40.78 10.84 22.04 165.6 3.960 5.071 9.687
rs10811661 0.10 Additive 3.80 21.2 0.861 13.6 3.61 7.35 55.2 1.62 1.69 3.95
Dominant 16.22 90.3 3.670 58.0 15.41 31.33 235.4 6.89 7.21 16.86
Recessive 4.11 22.9 0.931 14.7 3.91 7.95 59.7 1.75 1.83 4.28
rs2010963 0.35 Additive 2.39 13.3 0.541 8.5 2.27 4.62 34.7 1.02 1.06 2.49
Dominant 4.92 27.4 1.114 17.6 4.68 9.51 71.4 2.09 2.19 5.12
Recessive 3.27 18.2 0.739 11.7 3.10 6.31 47.4 1.39 1.45 3.40
rs659366 0.47 Additive 2.29 12.7 0.517 8.2 2.17 4.42 33.2 0.97 1.02 2.38
Dominant 3.89 21.7 0.880 13.9 3.70 7.51 56.5 1.65 1.73 4.04
Recessive 3.59 20.0 0.813 12.8 3.41 6.94 52.1 1.53 1.60 3.73
rs7896005 0.32 Additive 2.45 13.6 0.554 8.7 2.32 4.72 35.5 1.04 1.09 2.54
Dominant 5.32 29.6 1.204 19.0 5.06 10.28 77.2 2.26 2.37 5.53
Recessive 3.24 18.0 0.732 11.6 3.07 6.25 47.0 1.38 1.44 3.37
rs8192678 0.20 Additive 2.85 15.9 0.646 10.2 2.71 5.51 41.4 1.21 1.27 2.97
Dominant 8.23 45.9 1.863 29.4 7.82 15.91 119.5 3.50 3.66 8.56
Recessive 3.36 18.7 0.761 12.0 3.19 6.49 48.8 1.43 1.49 3.50

dbSNP – the single nucleotide polymorphism database, MAF – minor allele frequency, N – number of individuals per variable, SD – standard deviation, DBP – diastolic blood pressure, HbA1c – glycated haemoglobin, CHOL – cholesterol, HDL – high-density lipoprotein, SBP – systolic blood pressure, TRG – triglycerides, HOMA-IR – homeostasis model assessment of insulin resistance, BMI – body max index. All the traits were rank-based inverse normal transformed. Accuracy greater than 10% is marked in bold numbers.