Table X.
Effect βg calculated with Quanto software as percentage of the mean according to three models of inheritance
| Variable | DBP [mmHg] | Glucose [mg/dl] | HbA1c (%) | CHOL [mg/dl] | HDL [mg/dl] | SBP [mm Hg] | TRG [mg/dl] | HOMA-IR | BMI [kg/m2] | Insulin [mU/ml] | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbSNP | MAF | N | 406 | 406 | 408 | 406 | 406 | 406 | 406 | 355 | 409 | 357 |
| Mean | 77.4 | 102 | 11.2 | 179 | 49.8 | 143 | 154 | 2.20 | 31.3 | 6.96 | ||
| SD | 11.41 | 63.56 | 2.582 | 40.78 | 10.84 | 22.04 | 165.6 | 3.960 | 5.071 | 9.687 | ||
| rs10811661 | 0.10 | Additive | 4.9 | 20.9 | 7.7 | 7.6 | 7.3 | 5.1 | 35.7 | 73.6 | 5.4 | 56.8 |
| Dominant | 20.9 | 88.9 | 32.8 | 32.4 | 31.0 | 21.9 | 152.4 | 314.0 | 23.0 | 242.2 | ||
| Recessive | 5.3 | 22.6 | 8.3 | 8.2 | 7.9 | 5.6 | 38.7 | 79.6 | 5.8 | 61.4 | ||
| rs2010963 | 0.35 | Additive | 3.1 | 13.1 | 4.8 | 4.8 | 4.6 | 3.2 | 22.5 | 46.3 | 3.4 | 35.7 |
| Dominant | 6.4 | 27.0 | 9.9 | 9.8 | 9.4 | 6.7 | 46.3 | 95.3 | 7.0 | 73.5 | ||
| Recessive | 4.2 | 17.9 | 6.6 | 6.5 | 6.2 | 4.4 | 30.7 | 63.3 | 4.6 | 48.8 | ||
| rs659366 | 0.47 | Additive | 3.0 | 12.5 | 4.6 | 4.6 | 4.4 | 3.1 | 21.5 | 44.3 | 3.2 | 34.1 |
| Dominant | 5.0 | 21.3 | 7.9 | 7.8 | 7.4 | 5.3 | 36.6 | 75.3 | 5.5 | 58.1 | ||
| Recessive | 4.6 | 19.7 | 7.3 | 7.2 | 6.9 | 4.9 | 33.7 | 69.5 | 5.1 | 53.6 | ||
| rs7896005 | 0.32 | Additive | 3.2 | 13.4 | 4.9 | 4.9 | 4.7 | 3.3 | 23.0 | 47.4 | 3.5 | 36.5 |
| Dominant | 6.9 | 29.2 | 10.8 | 10.6 | 10.2 | 7.2 | 50.0 | 103.1 | 7.6 | 79.5 | ||
| Recessive | 4.2 | 17.7 | 6.5 | 6.5 | 6.2 | 4.4 | 30.4 | 62.7 | 4.6 | 48.3 | ||
| rs8192678 | 0.20 | Additive | 3.7 | 15.6 | 5.8 | 5.7 | 5.4 | 3.9 | 26.8 | 55.2 | 4.1 | 42.6 |
| Dominant | 10.6 | 45.1 | 16.6 | 16.4 | 15.7 | 11.1 | 77.4 | 159.4 | 11.7 | 123.0 | ||
| Recessive | 4.3 | 18.4 | 6.8 | 6.7 | 6.4 | 4.5 | 31.6 | 65.1 | 4.8 | 50.2 | ||
dbSNP – the single nucleotide polymorphism database, MAF – minor allele frequency, N – number of individuals per variable, SD – standard deviation, DBP – diastolic blood pressure, HbA1c – glycated haemoglobin, CHOL – cholesterol, HDL – high-density lipoprotein, SBP – systolic blood pressure, TRG – triglycerides, HOMA-IR – homeostasis model assessment of insulin resistance, BMI – body max index. All the traits were rank-based inverse normal transformed. Accuracy greater than 10% is marked in bold numbers.