Table III.

Correlation between candidate genotypes and clinical response (CCyR, MMR)

Referent genotype	N	CCyR at 6M Yes	CCyR at 6M No	P-value	CCyR at 12M Yes	CCyR at 12M No	P-value
CYP3A5*3 (rs776746):
C – C	98	59	39	0.06	89	9	±
T – C	13	4	9		12	1
T – T	1	0	1	0.05	0	1	0.90
CC vs. TC + TT
Referent genotype	N	MMR at 12M Yes	MMR at 12M No	P-value	MMR at 18M Yes	MMR at 18M No	P-value
CYP3A5*3 (rs776746):
C – C	98	54	44	0.54	70	28	0.31
T – C	13	7	6		9	4
T – T	1	0	1		0	1
CC vs. TC + TT				0.94			0.87
ABCG2 (rs2231142):
G – G	87	52	35	0.06	64	23	0.23
T – G	23	9	14		14	9
T – T	2	0	2		1	1
GG vs. TG + TT				0.06			0.15
TT vs. GT + GG				0.39			1

CCyR – complete hematologic response, MMR – major molecular response ± not evaluated (minor frequency nonresponders).