Table 4.
Tentative peak assignments for Raman saliva spectra
| Raman Shift/cm−1 | ΔI% | Major assignments | |
|---|---|---|---|
| Normal | Lung cancer | ||
| 423 ± 2 | 425 ± 3 | 89.41 | D‐glucose, deuterated glucose8, 9 |
| 643 ±3 | 650 ±2 | −24.97 | C‐H torsion, COO‐ wag; O‐C=O in plane deformation; C‐C‐C in phase deformation10, 11 |
| 672 ±2 | 672 ±1 | −90.82 | C–S stretch ofcysteine, cytosine/guanine |
| 732 ±3 | 726 ± 1 | 177.54 | C–S (protein)/CH2 rocking/adenine10, 11, 12, 13, 14 |
| 852 ±1 | 854 ±1 | −12.05 | Ring breathing mode of tyrosine and C–C stretch of proline ring10, 12, 15 |
| 923 ±2 | 924 ± 3 | −17.87 | C–C stretch of proline ring/glucose/lactic acid10 |
| 999 ±2 | 1000 ±2 | −48.84 | Symmetric ring breathing mode of phenylalanine10, 12, 14, 16 |
| 1030 ± 3 | 1026 ±1 | −60.93 | Stretching vibration of the ring, deformation in plane C‐H17 |
| 1046 ± 4, | 1050 ±2 | −66.47 | N‐ acetyl glucosamine, deuterated N‐acetyl glucosamine8, 9, 10 |
| 1268 ±2 | 1264 ± 3 | −2.28 | Amide III (C–N stretching mode of proteins, indicating mainly a‐helix conformation)10, 12 |
| 1449 ±2 | 1450 ±2 | −20.78 | Bending mode (C=C), phenylalanine, CH2 bending mode of proteins10, 11, 12, 13, 17 |
| 1600 ±2 | 1602 ±2 | −57.10 | C=C in‐plane bending mode of phenylalanine and tyrosine17, 18 |