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. 2018 Sep 22;148(11):1776–1785. doi: 10.1093/jn/nxy185

TABLE 3.

Serum cytokine and chemokine concentrations in 33 participants classified by adiposity and BMI1

Adiposity BMI
Normal adiposity, n = 12 High adiposity, n = 21 Normal weight, n = 8 Overweight, n = 14 Obese, n = 11
Cytokines
 Proinflammatory
  IL-1β, pg/mL 3.14 ± 2.31 2.78 ± 2.85 2.78 ± 2.27 3.73 ± 3.09 1.98 ± 2.09
  IL-6, pg/mL 2.53 ± 1.51 16.6 ± 57.9 2.33 ± 1.12 23.9 ± 70.6 2.28 ± 1.48
  TNF-α, pg/mL 10.2 ± 10.6 11.5 ± 15.2 6.31 ± 5.98 15.9 ± 17.5 8.32 ± 10.1
  G-CSF, pg/mL 94 ± 143 102 ± 168 59 ± 153 150 ± 181 62 ± 116
  IFN-γ, pg/mL 2.8 ± 3.7 54 ± 145 1.3 ± 1.5 81 ± 173 1.72 ± 2.67
 Anti-inflammatory
  IL-10, pg/mL 6.5 ± 3.4 25.2 ± 67.2 7.7 ± 4.7 32.5 ± 81.9 8.3 ± 9.2
  TGF-β1, ng/mL 39.3 ± 47.6 27.0 ± 31.4 31.7 ± 32.6 43.6 ± 50.6 15.8 ± 14.8
  TGF-β2, pg/mL 276 ± 176 311 ± 253 316 ± 680 334 ± 205 221 ± 184
  TGF-β3, pg/mL 140 ± 125 282 ± 354 92 ± 55 252 ± 301 305 ± 372
Chemokines
 IL-8, pg/mL 42.0 ± 31.8 41.0 ± 17.4 36.7 ± 12.8 50.1 ± 31.0 33.59 ± 12.7
 MCP-1, pg/mL 89.8 ± 127 69.2 ± 81 59 ± 57 102 ± 135 56 ± 64
 MIP-1α, pg/mL 13.1 ± 6.9 6.9 ± 5.1 8.55 ± 9.82 8.86 ± 6.43 9.99 ± 8.03
 MIP-1β, pg/mL 712 ± 1010 400 ± 278 348 ± 181 613 ± 930 507 ± 410
 RANTES, ng/mL 78.3 ± 53.6 91.8 ± 44.9 83.9 ± 52.2 95.3 ± 42.6 78.3 ± 53.7

1Values are means ± SDs. No differences were reported between adiposity or BMI classifications. G-CSF, granulocyte-colony–stimulating factor; MCP-1, monocyte chemoattractant protein 1; MIP, macrophage inflammatory protein; RANTES, regulated on activation, normal T-cell expressed and secreted.