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. 2018 Oct 25;9:1138. doi: 10.3389/fphar.2018.01138

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Copyright © 2018 Ma, Yu, Chen, Li, Ihsan, Tong, Huang and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The influence of sweroside on the intracellular Ca²⁺ increase induced by aconitine. (A) The effects of calcium overload were analyzed by flow cytometry using the fluorescent probe Fluo-3/AM; (B,C) Changes in the intracellular calcium ion levels in H9c2 cells treated with different drug Hank’s media; (D) Effects of pretreatment with sweroside and aconitine-stimulation on [Ca²⁺]_i in H9c2 cells. ^∗P < 0.05 and ^∗∗∗P < 0.001 compared between two groups.