Figure 5.
Effects of Intralipid® (lipid emulsion, LE) on doxorubicin-induced oxidative stress in H9c2 rat cardiomyoblasts. H9c2 cells were treated with doxorubicin alone (10−5 M) for 24 h, LE (0.25%) for 1 h followed by doxorubicin (10−5 M) for 24 h, or LE (0.25%) alone for 25 h. The levels of malondialdehyde (MDA, A), a marker of lipid peroxidation, superoxide dismutase (SOD, B) activity and catalase (CAT, C) activity in different treatment groups were measured and compared with those in the control. Data are presented as the mean ± SD (N = 3). * p< 0.001 versus control. † p < 0.001 versus doxorubicin alone.