Table 2.
Distribution of the TM transporters based on the transporter classification database into class and subclass in E. histolytica.
| TC Class | Class Description | No. of Proteins | uncharP * | TC Subclass | Subclass Description | No. of Proteins |
|---|---|---|---|---|---|---|
| 1 | Channel | 80 | 27 | 1.A | α-Type channels | 45 |
| 1.C | Pore-forming toxins | 13 | ||||
| 1.F | Vesicle Fusion Pore | 14 | ||||
| 1.I | Membrane-bounded Channels | 1 | ||||
| 1.N | Cell Fusion Pores | 3 | ||||
| 1.P | Non-Envelop Virus Penitration Complex | 4 | ||||
| 2 | Secondary carriers | 134 | 36 | 2.A | Porters (uniporters, symporters, antiporters) | 131 |
| 2.C | Ion-gradient-driven energizers | 1 | ||||
| 2.D | Transcompartment Lipid Carrier | 2 | ||||
| 3 | Primary active transporter | 86 | 14 | 3.A | P-P-bond-hydrolysis-driven transporters | 82 |
| 3.D | Oxidoreduction-driven transporters | 4 | ||||
| 4 | Group Transporters | 12 | 0 | 4.D | Polysaccharide Synthase/Exporters | 3 |
| 4.F | Choline/EthanolaminePhosphotransferase1 | 9 | ||||
| 5 | TM electron carriers | 2 | 2 | 5.B | Transmembrane 1-electron transfer carriers | 2 |
| 8 | Accessory factors involved in transport | 66 | 17 | 8.A | Auxiliary transport proteins | 66 |
| 9 | Incompletely characterized transport systems | 166 | 45 | 9.A | Recognized transporters of unknown biochemical mechanism | 48 |
| 9.B | Putative transport proteins | 118 | ||||
| Unclassified | 146 | 83 |
Transporter classes 6 and 7 have not been assigned in the Transport Classification (TC) system, and they are therefore absent. * uncharP—Uncharacterized proteins identified as TM proteins.