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. 2018 Sep 21;12(11):1895–1916. doi: 10.1002/1878-0261.12356

Figure 5.

Figure 5

S100A10 mRNA expression is regulated by differential CpG site methylation. S100A10 mRNA (A,B,C) and protein (D,E,F) changes in Panc 10.05 (A,D), Panc‐1 (B,E), and AsPC‐1 (C,F) in response to 10 μm decitabine (DAC) for 72 h. Global and CpG‐specific methylation of the 24 CpGs in the S100A10 promoter in Panc 10.05 (G,J), Panc‐1 (H,K), and AsPC‐1 (I,L). Graphs G–I represent the averages of percentages of all 24 sites in each cell line. Graphs J–L represent the percentage methylated of cytosines of a specific CpG site within each sample. Significance was determined using unpaired t‐tests. Data are represented as mean ± SD.