Table 2.
Populations | Patient No. | miR‐16 | miR‐21 | miR‐23a | miR‐92a | miR‐93 | miR‐100 | miR‐126 | miR‐200b | miR‐200c | miR‐223 | miR‐320 | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EOC vs healthya | 106 vs 29 | Fold change | 0.5 | 2.3 | 1.0 | 1.2 | 0.5 | 2.0 | 0.6 | 5.2 | 4.9 | 0.6 | 1.5 | |
P‐value | 0.009 | 0.0001 | 1.000 | 0.148 | 0.014 | 0.034 | 0.012 | 0.008 | 0.143 | 0.029 | 0.034 | |||
EOC vs cystadenomaa | 106 vs 8 | Fold change | 0.9 | 3.0 | 4.6 | 2.0 | 0.9 | 12.4 | 0.5 | 2.3 | 3.5 | 0.7 | 1.5 | |
P‐value | 1.00 | 0.100 | 0.009 | 0.009 | 1.000 | 0.210 | 0.210 | 0.261 | 0.725 | 0.976 | 0.630 | |||
Cystadenoma vs healthya | 8 vs 29 | Fold change | 0.6 | 0.8 | 0.2 | 0.6 | 0.6 | 0.2 | 1.1 | 2.3 | 1.4 | 0.9 | 1.0 | |
P‐value | 0.478 | 0.839 | 0.008 | 0.034 | 0.770 | 0.177 | 1.000 | 0.229 | 1.000 | 1.000 | 1.000 | |||
Clinical parameters in EOC patients | ||||||||||||||
Recurrencea | Yes | 48 | Fold change | 0.5 | 1.1 | 1.0 | 0.8 | 0.6 | 1.4 | 1.0 | 1.3 | 1.1 | 0.8 | 0.9 |
No | 54 | P‐value | 0.001 | 0.648 | 0.845 | 0.073 | 0.05 | 0.224 | 0.780 | 0.710 | 0.841 | 0.366 | 0.717 | |
Histologya | Serous | 90 | Fold change | 0.7 | 0.5 | 0.7 | 0.7 | 0.7 | 0.6 | 0.7 | 0.7 | 0.6 | 0.7 | 0.7 |
Others | 13 | P‐value | 0.432 | 0.026 | 0.285 | 0.010 | 0.413 | 0.192 | 0.162 | 0.686 | 0.289 | 0.177 | 0.190 | |
Gradinga | G1–2 | 24 | Fold change | 0.5 | 0.8 | 1.0 | 0.8 | 0.7 | 1.3 | 1.0 | 4.1 | 0.8 | 1.2 | 0.8 |
G3 | 69 | P‐value | 0.019 | 0.504 | 0.995 | 0.150 | 0.200 | 0.341 | 0.946 | 0.144 | 0.524 | 0.366 | 0.226 | |
CA125b | P‐value | 0.325 | 0.377 | 0.637 | 0.124 | 0.415 | 0.156 | 0.762 | 0.002 | 0.003 | 0.835 | 0.363 |
a P‐values are calculated by two‐tailed Student's t‐test. b P‐values are calculated by bivariate analyses of Spearman rho test.