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. 2018 Oct 9;12(11):1935–1948. doi: 10.1002/1878-0261.12371

Table 2.

P‐values with the corresponding fold changes of exosomal miRNAs in bold

Populations Patient No. miR‐16 miR‐21 miR‐23a miR‐92a miR‐93 miR‐100 miR‐126 miR‐200b miR‐200c miR‐223 miR‐320
EOC vs healthya 106 vs 29 Fold change 0.5 2.3 1.0 1.2 0.5 2.0 0.6 5.2 4.9 0.6 1.5
P‐value 0.009 0.0001 1.000 0.148 0.014 0.034 0.012 0.008 0.143 0.029 0.034
EOC vs cystadenomaa 106 vs 8 Fold change 0.9 3.0 4.6 2.0 0.9 12.4 0.5 2.3 3.5 0.7 1.5
P‐value 1.00 0.100 0.009 0.009 1.000 0.210 0.210 0.261 0.725 0.976 0.630
Cystadenoma vs healthya 8 vs 29 Fold change 0.6 0.8 0.2 0.6 0.6 0.2 1.1 2.3 1.4 0.9 1.0
P‐value 0.478 0.839 0.008 0.034 0.770 0.177 1.000 0.229 1.000 1.000 1.000
Clinical parameters in EOC patients
Recurrencea Yes 48 Fold change 0.5 1.1 1.0 0.8 0.6 1.4 1.0 1.3 1.1 0.8 0.9
No 54 P‐value 0.001 0.648 0.845 0.073 0.05 0.224 0.780 0.710 0.841 0.366 0.717
Histologya Serous 90 Fold change 0.7 0.5 0.7 0.7 0.7 0.6 0.7 0.7 0.6 0.7 0.7
Others 13 P‐value 0.432 0.026 0.285 0.010 0.413 0.192 0.162 0.686 0.289 0.177 0.190
Gradinga G1–2 24 Fold change 0.5 0.8 1.0 0.8 0.7 1.3 1.0 4.1 0.8 1.2 0.8
G3 69 P‐value 0.019 0.504 0.995 0.150 0.200 0.341 0.946 0.144 0.524 0.366 0.226
CA125b P‐value 0.325 0.377 0.637 0.124 0.415 0.156 0.762 0.002 0.003 0.835 0.363

a P‐values are calculated by two‐tailed Student's t‐test. b P‐values are calculated by bivariate analyses of Spearman rho test.