Skip to main content
. 2018 Oct 15;12(11):1856–1870. doi: 10.1002/1878-0261.12384

Figure 1.

Figure 1

Metformin suppresses CRC cell growth and colony formation. (A) Metformin inhibits HCT116 and HT29 cell growth in a dose‐dependent manner. (B) Metformin arrests the HCT116 and HT29 cells at G1 phase. (C) Metformin at 2 mm completely abrogates the colony formation ability of HCT116 and HT29 cells. (D) Metformin reduces colony formation of CRC cells in a dose‐dependent fashion. The proliferation data are presented as the means ± SD of values obtained in 3 independent experiments. Student's t‐test was used to assess significance relative to vehicle control. *P < 0.05.