Table 1.
Patient characteristics and demographics at baseline.
| Patients | Audencel Group | Control Group |
|---|---|---|
| N | 34 | 42 |
| Sex | ||
| female | 12 | 13 |
| male | 22 | 29 |
| Age (years) | 54.6 | 54 |
| ECOG | ||
| 0 | 14 (41%) | 14 (33%) |
| 1 | 20 (59%) | 21 (50%) |
| 2 | 0 | 7 (17%) |
| >2 | 0 | 0 |
| Surgery | ||
| Gross total resection | 24 (71%) | 35 (83%) |
| Partial resection | 10 (29%) | 7 (17%) |
| Number of target lesions at post OP screening | ||
| 0 | 24 (71%) | 35 (83%) |
| 1 | 10 (29%) | 7 (17%) |
| Number of non-target lesions at post-OP screening | ||
| 0 | 34 | 42 |
| >1 | 0 | 0 |
| Anti-epileptic drugs | ||
| Non enzyme-inducing AEDs | 11 | 18 |
| Enzyme inducing AEDs | 0 | 0 |
| MGMT promoter methylation | N = 20 samples measured | N = 17 samples measured |
| methylated | 7/20 35% | 6/17 35% |
| unmethylated | 13/20 65% | 11/17 65% |
ECOG: Eastern Cooperative Oncology Group; OP: operation; AED: anit-epileptic drugs; MGMT: O-6-methylguanine-DNA methyltransferase.