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. 2018 Sep 24;15(10):2092. doi: 10.3390/ijerph15102092

Table 4.

Multivariate analysis on the use of epidural analgesia, type of delivery, duration of the second stage of labor and its link with neonatal morbidity in population 2.

Umbilical Artery pH < 7.10 Aj. OR * CI 95% p-Value
Use of EA 0.89 0.33, 2.37 0.813
Type of delivery
(Ref. Normal Vaginal)
Instrumental delivery 2.68 1.15, 6.27 0.023
C-section 2.32 0.50, 10.73 0.282
Second stage of labor duration (Ref. < 1 h)
1–2 h 0.74 0.31, 1.78 0.497
2–3 h 0.83 0.32, 2.16 0.702
>3 h 0.81 0.48, 2.34 0.699
Apgar at 5 min < 7 Aj. OR * CI 95% p-Value
Use of EA NC NC 0.933
Type of delivery
(Ref. Normal Vaginal)
Instrumental delivery 4.11 0.59, 28.70 0.154
C-section 8.23 0.68, 100.45 0.999
Second stage of labor duration (Ref. < 1 h)
1–2 h NC NC 0.992
2–3 h 0.61 0.09, 4.09 0.607
>3 h 0.28 0.02, 3.28 0.311
Advanced neonatal resuscitation Aj. OR * CI 95% p-Value
Use of EA NC NC 0.993
Type of delivery (Ref. Normal Vaginal)
Instrumental delivery 2.44 1.17, 5.08 0.017
C-section 2.56 0.71, 9.24 0.151
Second stage of labor duration (Ref. < 1 h)
1–2 h 0.90 0.46, 1.78 0.766
2–3 h 0.66 0.29, 1.50 0.321
>3 h 0.38 0.13-1.10 0.075
Composite morbidity Aj. OR * CI 95% p-Value
Use of EA 1.80 0.75, 4.37 0.191
Type of delivery (Ref. Normal Vaginal)
Instrumental delivery 2.86 1.59, 5.12 <0.001
C-section 2.20 0.73, 6.65 0.161
Second stage of labor duration (Ref. < 1 h)
1–2 h 0.85 0.49, 1.50 0.580
2–3 h 0.73 0.38, 1.40 0.340
>3 h 0.52 0.24, 1.14 0.112

C-section = Caesarean Section; EA=Analgesia Epidural; Ref= Reference category. * Aj. OR: Odds Ratio adjusted with binary logistic regression by use of epidural analgesia, type of delivery, second stage of labor duration, maternal age, birth weight, gestational age, parity, previous caesarean section, and first stage of labor duration.