Table 1.
Demographic, clinical, and hormonal parameters of POI and control groups. Data shown as mean ± SD; a Student’s t-test; b Mann-Whitney U test (p-values < 0.05 are bolded). BMI—body mass index; FSH—follicle stimulating hormone; LH—luteinizing hormone; E2—17β-estradiol; PRL—prolactin, T—testosterone; DHEA-S—dehydroepiandrosterone sulfate; TSH—thyroid stimulating hormone; fT4—thyroxine.
| POI Women (n = 56) | Controls (n = 68) | p-Value | |
|---|---|---|---|
| Age (year) b | 30.7 ± 6.9 | 27.3 ± 4.5 | <0.001 |
| BMI (kg/m2) b | 23.54 ± 4.55 | 28.62 ± 5.30 | <0.001 |
| FSH (U/L) b | 97.57 ± 42.30 | 5.82 ± 2.19 | <0.001 |
| LH (U/L) b | 50.93 ± 26.62 | 13.88 ± 9.68 | <0.001 |
| E2 (pg/mL) b | 21.45 ± 43.07 | 172.64 ± 134.71 | <0.001 |
| T (ng/mL) b | 0.27 ± 0.14 | 0.55 ± 0.20 | <0.001 |
| PRL (ng/mL) b | 10.08 ± 4.83 | 17.26 ± 9.18 | <0.001 |
| DHEA-S (umol/L) a | 6.54 ± 2.86 | 7.83 ± 3.30 | 0.046 |
| TSH (uIU/mL) b | 2.46 ± 1.53 | 2.31 ± 1.04 | 0.93 |
| fT4 (ng/dL) a | 1.32 ± 0.22 | 1.29 ± 0.17 | 0.34 |