Fig. 4.

From composition to glycoprotein features. An interactive way of extracting glycoprotein features from glycan compositions combining published data and ad hoc tools (1). A list of compositions is input in GlyConnect, which retrieves all the proteins reported as having these compositions attached to them (on the left) and reported glycan structures corresponding to this composition (on the right) annotated in this knowledge base. Glycan structures can be further processed to extract contained glycan epitopes using EpitopeXtractor (2a). Glycoepitope results can be mapped on Glydin', an interactive epitope network (3a). Glydin' aggregates glycan epitopes from four different sources (databases and literature reviews) and provides links to the original information. When epitopes are taken from SugarBindDB, further information on the pathogens can be browsed (4a).