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. 2018 Oct 15;9(10):495. doi: 10.3390/genes9100495

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Approximation of the contribution of HBV genotypes to global burden of chronic HBV infection. (A) Estimation of the number of chronic infections with each genotype per world region. *: Oceania includes pooled data of Australia/New Zealand, Melanesia, Micronesia, and Polynesia. (B) Approximation of the genotype distribution within global chronic HBV infections. Values <2% are given with two decimals to prevent distortion of genotype distribution. Recombinant/co-infection: infection with an inter-genotype recombinant or with more than one HBV genotype; Undefined: genotype allocation not possible.