Table 1.
Cytoprotective effects of selected natural compounds.
| Compounds | Mechanism of Cytoprotection | References |
|---|---|---|
| CAPE | Induction of HO-1 | Wang et al. [8], Scapagnini et al. [9] |
| Inhibition of IL5 and IFNγ production | Wang et al. [10] | |
| Tyrosine kinase inhibitor | Patel et al. [11] | |
| Inhibition of NF-κB activation | Natarajan et al. [12] | |
| CDDO-Im | Induction of heat shock protein family Activation of MAP2K1 and DUSP1 Induction of glutathione (GSH) Activation of Nrf2/ARE pathway and induction of Nrf2 downstream genes |
Wang et al. [8] Bynum et al. [13] Speen et al. [14] Reisman et al. [15], Liby et al. [16] |
| Resveratrol | Upregulating HO-1 and activation of PI3K/Akt/Nrf2 pathway | Hui et al. [17], Jin et al. [18] |
| Inhibition of caspase activation and proteolytic cleavage of tau at Asp421 | Means et al. [19] | |
| Increasing SIRT1 deacetylate activity | Wang et al. [20] | |
| Suppression of Wnt/β-catenin signaling | Xu et al. [21], Geng et al. [22], Xie et al. [23] | |
| Curcumin | Induction of HO-1and activation of Nrf2/ARE signaling | Motterlini et al. [24], Balogun et al. [25] |
| Induction of Glutathione Biosynthesis, Inhibition of NF-κB Activation and Interleukin-8 Release | Biswas et al. [26] | |
| Suppression of STAT-3 and Wnt/β-catenin and activation of PPAR-γ | Shehzad et al. [27] |