Table 3.
Adjusted Cox Proportional Hazard Model for overall survival.
| Variable | Hazard Ratio | 95% CI | p Value |
|---|---|---|---|
| Age | 1.04 | 1.00–1.07 | 0.029 |
| Woman | 0.48 | 0.26–0.89 | 0.019 |
| Patient-reported education | |||
| No diploma (reference) | |||
| High school | 0.42 | 0.22–0.81 | 0.009 |
| Bachelor degree | 0.41 | 0.16–1.06 | 0.07 |
| >Bachelor | 0.50 | 0.14–1.70 | 0.26 |
| Patient-reported financial situation | |||
| Not at all or not very comfortable (reference) | |||
| Moderately comfortable | 1.42 | 0.58–3.45 | 0.44 |
| Rather or very comfortable | 1.27 | 0.46–3.57 | 0.65 |
| Type and severity of cancer | |||
| Stage I, II or III (NSCL or SCL) (reference category) | |||
| Stage IV (NSCL or SCL) | 3.14 | 1.22–8.09 | 0.018 |
| Mesothelioma (no stage assigned) | 3.30 | 1.22–8.91 | 0.018 |
| Karnofsky index 60–70 (compared to >70) | 2.53 | 0.84–7.59 | 0.10 |
| Time since diagnosis and inclusion in the study | 0.98 | 0.84–1.14 | 0.75 |
| Charlson index of comorbidities | 1.02 | 0.88–1.17 | 0.80 |
| Mutation (ALK, EGFR, ROS vs. none of them) | 1.40 | 0.64–3.06 | 0.40 |
| Metastases | 0.92 | 0.38–2.25 | 0.85 |
| Cancer-related emotional distress | 1.06 | 1.01–1.12 | 0.03 |
| Emotional skills | 1.57 | 0.87–2.85 | 0.14 |
| Patient-reported physician empathy | - | - | - |
| Type of consultation (bad news vs. follow-up) | - | - | - |
| Empathy * type-of-consultation (interaction) | 0.022 | ||
| Empathy in bad news consultations | 1.06 | 1.01–1.12 | 0.024 |
| Empathy in follow-up consultations | 0.96 | 0.90–1.03 | 0.24 |
NSCL: Non-small cell lung cancer; SCL: Small cell lung cancer; n = 143 (due to missing data in some variables), -2LL = 587.8, Akaike Information Criterion (AIC) = 625.8, Schwarz Bayesian Criterion (SBC) = 668.8. EGFR: Epidermal Growth Factor Receptor; ALK: Anaplastic Lymphoma Kinase; ROS: ROS proto-oncogene 1, receptor tyrosine kinase.