Table 5.

The clinical trials of oncolytic viruses in patients with breast cancer.

Oncolytic Virus	Clinical Trial Phase	Administration Route	Combination	Status	Trial No.	Reference
T-VEC (Talimogene laherparepvec)	I	IT	----	Completed	PMID17121894	[29]
HF10 (canerpaturev—C-REV)	IIT	IT	----	Completed	PMID16865590	[98,99]
ONYX-015	I	IT	Enbrel	Completed	PMID17704755	[100]
ICOVIR-7	I	IT	----	Completed	PMID20501623	[101]
Vaccinia Virus (VVDD)	I	IT	----	Completed	PMID25292189	[102]
PV701		IV	----	Completed	PMID16638865	[103]
CVA21	I	IT	----	Completed Not reported	NCT00636558
Measles Virus (MV)-NIS	I	IT	----	Ongoing	NCT01846091
	I	IT	----	Recruiting	NCT01376505
Pelareorep (Reolysin®)	I	IV	----	Completed	PMID19572105	[104]
	II	IV	Paclitaxel	Completed	NCT01656538	[105]