Table 1.
Characteristics of head and neck squamous cell carcinoma (HNSCC) patients with curative-intent treatment.
| Number of Patients | |||
|---|---|---|---|
| NLR < 3 | NLR ≥ 3 | p-Value | |
| Patient | 108 | 119 | |
| Age | |||
| <55 (median) | 52 | 53 | 0.58 |
| ≥55 | 56 | 66 | |
| Differentiation | 0.38 | ||
| Well differentiated | 39 | 39 | |
| Moderately differentiated | 38 | 41 | |
| Poorly differentiated | 23 | 32 | |
| Unknown | 8 | 7 | |
| Tumor stage | 0.073 | ||
| ≤T2 | 61 | 53 | |
| T3–T4 | 47 | 66 | |
| Clinical LN involvement | 0.87 | ||
| Negative | 42 | 45 | |
| Positive | 66 | 74 | |
| Tx policy | 0.98 | ||
| Definite CCRT | 31 | 34 | |
| Surgery +/− neoadjuvant/adjuvant Tx | 77 | 85 | |
| Location | 0.23 | ||
| Oral cavity | 72 | 88 | |
| Pharynx (Oro-Hypo) | 36 | 31 | |
| Loco-regional recurrence | <0.001 * | ||
| Control | 88 | 65 | |
| Failure | 20 | 54 | |
| Distant metastasis | 0.146 | ||
| Negative | 102 | 108 | |
| Positive | 6 | 13 | |
| Status | <0.001 * | ||
| Alive | 86 | 66 | |
| Dead | 22 | 53 | |
NLR: neutrophil-to-lymphocyte ratio; CCRT: radiotherapy and chemotherapy; LN: lymph node; Tx: treatment; *: Statistically significant covariate; T: tumor.