Table 2.
Number of Patients | |||
---|---|---|---|
ALDH1 (−) | ALDH1 (+) | p-Value | |
Patients | 118 | 109 | |
Age | |||
<55 (median) | 56 | 49 | 0.71 |
≥55 | 62 | 60 | |
Differentiation | 0.38 | ||
Well differentiated | 44 | 34 | |
Moderately differentiated | 39 | 40 | |
Poorly differentiated | 27 | 28 | |
Unknown | 8 | 7 | |
Tumor stage | 0.13 | ||
≤T2 | 65 | 49 | |
T3–T4 | 53 | 60 | |
Clinical LN involvement | 0.016 * | ||
Negative | 54 | 33 | |
Positive | 64 | 76 | |
Tx policy | 0.42 | ||
Definite CCRT | 35 | 34 | |
Surgery +/− neoadjuvant/adjuvant Tx | 83 | 75 | |
Location | 0.96 | ||
Oral cavity | 72 | 77 | |
Pharynx (Oro-Hypo) | 36 | 32 | |
NLR | <0.001 * | ||
<3 | 89 | 19 | |
≥3 | 29 | 90 | |
Loco-regional recurrence | <0.001 * | ||
Control | 104 | 49 | |
Failure | 14 | 60 | |
Distant metastasis | 0.019 * | ||
Negative | 113 | 95 | |
Positive | 5 | 14 | |
Status | <0.001 * | ||
Alive | 96 | 56 | |
Dead | 22 | 53 |
ALDH1. aldehyde dehydrogenase 1; *: Statistically significant covariate.