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. 2018 Sep 20;7(10):294. doi: 10.3390/jcm7100294

Table 2.

Characteristics of head and neck squamous cell carcinoma (HNSCC) patients with curative-intent treatment.

Number of Patients
ALDH1 (−) ALDH1 (+) p-Value
Patients 118 109
Age
<55 (median) 56 49 0.71
≥55 62 60
Differentiation 0.38
Well differentiated 44 34
Moderately differentiated 39 40
Poorly differentiated 27 28
Unknown 8 7
Tumor stage 0.13
≤T2 65 49
T3–T4 53 60
Clinical LN involvement 0.016 *
Negative 54 33
Positive 64 76
Tx policy 0.42
Definite CCRT 35 34
Surgery +/− neoadjuvant/adjuvant Tx 83 75
Location 0.96
Oral cavity 72 77
Pharynx (Oro-Hypo) 36 32
NLR <0.001 *
<3 89 19
≥3 29 90
Loco-regional recurrence <0.001 *
Control 104 49
Failure 14 60
Distant metastasis 0.019 *
Negative 113 95
Positive 5 14
Status <0.001 *
Alive 96 56
Dead 22 53

ALDH1. aldehyde dehydrogenase 1; *: Statistically significant covariate.