Table 4.
Adjusted hazard ratio (HR) of determining factors associated with overall survival (OS) of patients with head and neck squamous cell carcinoma (HNSCC).
| Variable | HR | 95% CI | p-Value |
|---|---|---|---|
| Age | |||
| <50 | Ref | ||
| ≥50 | 1.51 | 0.92–2.47 | 0.1 |
| Differentiation | |||
| Well–Moderately differentiated | Ref | ||
| Poorly differentiated. | 0.77 | 0.43–1.36 | 0.36 |
| Clinical T stage | |||
| ≥T2 | Ref | ||
| T3–T4 | 0.85 | 0.54–1.36 | 0.5 |
| Clinical N stage | |||
| N 0 | Ref | ||
| N (+) | 1.49 | 0.9–2.47 | 0.12 |
| NLR | |||
| <3 | Ref | ||
| ≥3 | 2.69 | 1.62–4.46 | <0.001 * |
| Treatment | |||
| Definite CCRT | Ref | ||
| Surgery +/− neoadjuvant/adjuvant Tx | 0.44 | 0.24–0.79 | 0.006 * |
CI: Confidence Interval; Ref: Reference Group; N: Lymph node staging; *: Statistically significant covariate.