Table 6.
Adjusted hazard ratio (HR) of determining factors associated with overall survival (OS) of patients with head and neck squamous cell carcinoma (HNSCC).
| Variable | HR | 95% CI | p-Value |
|---|---|---|---|
| Age | |||
| <50 | Ref | ||
| ≥50 | 1.36 | 0.84–2.12 | 0.21 |
| Differentiation | |||
| Well–Moderately differentiated | Ref | ||
| Poorly differentiated | 0.79 | 0.45–1.39 | 0.42 |
| Clinical T stage | |||
| ≤T2 | Ref | ||
| T3–T4 | 1.01 | 0.62–1.60 | 0.98 |
| Clinical N stage | |||
| N 0 | Ref | ||
| N (+) | 1.17 | 0.71–1.93 | 0.53 |
| ALDH1 | |||
| Negative | Ref | ||
| Positive | 4.1 | 2.43–6.92 | <0.001 * |
| Treatment | |||
| Definite CCRT | Ref | ||
| Surgery +/− neoadjuvant/adjuvant Tx | 0.48 | 0.27–0.87 | 0.015 * |
*: Statistically significant covariate.