Table 8.
Adjusted hazard ratio (HR) of determining factors associated with overall survival (OS) of patients with neck squamous cell carcinoma (HNSCC).
| Variable | HR | 95% CI | p-Value |
|---|---|---|---|
| Age | |||
| <50 | Ref | ||
| ≥50 | 0.71 | 0.32–1.55 | 0.39 |
| Differentiation | |||
| Well–Moderately differentiated | Ref | ||
| Poorly differentiated | 0.44 | 0.18–1.06 | 0.07 |
| Clinical T stage | |||
| ≤T2 | Ref | ||
| T3–T4 | 1.04 | 0.44–2.48 | 0.93 |
| Clinical N stage | |||
| N 0 | Ref | ||
| N (+) | 1.19 | 0.49–2.90 | 0.70 |
| MDSC | |||
| Low | Ref | ||
| High | 6.19 | 2.34–18.0 | <0.001 * |
| Treatment | |||
| Definite CCRT | Ref | ||
| Surgery +/− neoadjuvant/adjuvant Tx | 0.43 | 0.19–0.98 | 0.044 * |
*: Statistically significant covariate.