Table 9.
Adjusted hazard ratio (HR) of determining factors associated with disease failure of patients with neck squamous cell carcinoma (HNSCC).
| Variable | HR | 95% CI | p-Value |
|---|---|---|---|
| Age | |||
| <50 | Ref | ||
| ≥50 | 0.70 | 0.34–1.40 | 0.31 |
| Differentiation | |||
| Well–Moderately differentiated | Ref | ||
| Poorly differentiated | 0.61 | 0.29–1.25 | 0.18 |
| Clinical T stage | |||
| ≤T2 | Ref | ||
| T3–T4 | 1.28 | 0.60–2.76 | 0.52 |
| Clinical N stage | |||
| N 0 | Ref | ||
| N (+) | 1.59 | 0.68–3.75 | 0.29 |
| ALDH1 | |||
| Negative | Ref | ||
| Positive | 5.31 | 2.23–12.62 | <0.001 * |
| Treatment | |||
| Definite CCRT | Ref | ||
| Surgery +/− neoadjuvant/adjuvant Tx | 0.39 | 0.19–0.82 | 0.012 * |
*: Statistically significant covariate.