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BLI-3/Duox activation and function. On the left side are the inputs that either directly or indirectly activate (arrows or green text) or inhibit (T-bar or red text) the BLI-3/Duox activity. On the right side are the outputs that are mediated by the BLI-3-generated ROS. Evidence and explanations are in the main text of this review. Pyrroloquinoline quinone (PQQ), diphenyleneiodonium (DPI).
