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. 2018 Sep 22;10(10):349. doi: 10.3390/cancers10100349

Figure 3.

Figure 3

Cancer results from mutations involving genetic factors and epigenetic modifications affecting gene expression, a multitude of risk factors, lifestyle, microbiota resulting in vast biochemical changes that affect cell multiplication, survival, apoptosis, and evading surveillance by the immune system, culminating in cancer and metastasis.