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. 2018 Oct 11;7(10):343. doi: 10.3390/jcm7100343

Table 2.

Incidence and risk of new-onset DM and mortality between ESRD dialysis cohort and the comparison cohort.

Events (n/N) Incidence Rate a cHR (95% CI) p Value aHR b (95% CI) p Value aHR c (95% CI) p Value
New-onset DM
Cohorts
Comparison cohort 869/8912 15.88 (14.83–16.94) 1.00 1.00 1.00
ESRD dialysis cohort 109/2228 9.15 (7.43–10.87) 0.50 (0.41–0.61) <0.0001 0.49 (0.39–0.61) <0.0001 0.56 (0.46–0.69) <0.0001
Categorized dialysis type at start
Comparison cohort 869/8912 15.88 (14.83–16.94) 1.00 1.00 1.00
ESRD dialysis cohort
PD 12/136 15.98 (6.94–25.03) 0.94 (0.53–1.66) 0.82 0.84 (0.47–1.51) 0.56 0.93 (0.52–1.64) 0.8
HD 97/2092 8.69 (6.96–10.42) 0.47 (0.38–0.58) <0.0001 0.46 (0.37–0.58) <0.0001 0.54 (0.44–0.66) <0.0001
Mortality
Cohorts
Comparison cohort 1250/8912 22.85 (21.58–24.11) 1.00 1.00 1.00
ESRD dialysis cohort 671/2228 56.33 (52.06–60.59) 2.54 (2.31–2.79) <0.0001 2.32 (2.07–2.60) <0.0001 2.25 (2.00–2.47) <0.0001
Categorized dialysis type at start
Comparison cohort 1250/8912 22.85 (21.58–24.11) 1.00 1.00 1.00
ESRD dialysis cohort
PD 29/136 38.62 (24.57–52.68) 1.67 (1.16–2.40) 0.006 2.37 (1.61–3.51) <0.0001 2.50 (1.72–3.63) <0.0001
HD 642/2092 57.52 (53.07–61.97) 2.60 (2.36–2.86) <0.0001 2.32 (2.07–2.60) <0.0001 2.21 (1.99–2.46) <0.0001

Abbreviations: ESRD, end-stage renal disease; aHR, adjusted hazard ratio; cHR, crude hazard ratio; CI, confidence interval. a per 1000 person-years. b Adjusted for all variables in Table 1 by Cox proportional hazard model with Fine and Grey’s method to consider death as a competing risk. c Adjusted for all variables in Table 1 by stepwise Cox proportional hazard model (SLENTRY = 0.15 and SLSTAY = 0.15) with cause-specified method to consider death as a competing risk.