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Receiver operating characteristic (ROC) curves for serum concentrations of uPAR on admission in prediction of SAP (A), vital organ failure (MMSS ≥2 points) (B), and ICU transfer or death (C). For comparison, ROC curves are shown for other proposed single biomarkers of AP severity measured on admission: Interleukin-6 (IL-6), C-reactive protein (CRP), procalcitonin, D-dimer, and soluble fms-like tyrosine kinase-1 (sFlt-1).
